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PHTHALAMIDE FOR SYNTHESIS

Product Description | Product Application | Product Notes| Product DOSE
Synthesis of phthalimides. An efficient and simple method enables the N-alkylation of aromatic cyclic imides using cesium carbonate as the base in anhydrous N,N-dimethylformamide at low temperatures (20-70˚C).The method is compatible with base labile functional groups.
Code:
RXSOL-60-6605-237
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PHTHALAMIDE FOR SYNTHESIS

Short Description:
PHTHALAMIDE FOR SYNTHESIS
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PHTHALAMIDE FOR SYNTHESIS
Application:
The Gabriel Synthesis Uses A “Protected” Amine (Phthalimide) In An SN2 Reaction That Does Not Undergo Over-Alkylation. ... In phthalimide, a nitrogen is flanked by two carbonyl groups. This means tha [+] Read More...
Using Procedure:
Potassium phthalimide is a -NH2-synthon which allows the preparation of primary amines by reaction with alkyl halides. After alkylation, the phthalimid is not nucleophile and does not react anymore. Product is cleaved by reaction with base or hydrazine, which leads to a stable cyclic product.
Note:
The Gabriel method generally doesn't work with secondary alkyl halides. Another disadvantage of this synthesis is that using acidic/basic hydrolysis gives a low yield whereas the usage of hydrazine can make the conditions of the synthesis relatively harsh.
Technical Specifications:
PHTHALAMIDE FOR SYNTHESIS manufacturers, suppliers, exporters in Mumbai, Gandhidham, Kolkata, Varanasi, Visakhapatnam, Chennai, Fujairah, Dubai, Canada BC, Barka, Sohar, Muscat, Oman.
Lab chemicals manufacturers, suppliers, exporters in India, UAE Middle East, Barka, Sohar, Muscat, Oman, Canada.
 
PHTHALAMIDE FOR SYNTHESIS is available in small packing as well as in bulk. Buy premium quality PHTHALAMIDE FOR SYNTHESIS  and other lab chemicals from one of the most trusted brands.
PHTHALAMIDE FOR SYNTHESIS
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